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NCT07696858
Short-Term Tocolysis in Preterm Labor
Conditions: Preterm Labor
Sex: Female
Ages: 18 Years – 45 Years
Healthy volunteers: No
Enrollment: 100
Sponsor: Sohag University
Summary
The aim of this study is to identify independent prognostic factors associated with the success of short-term tocolysis, defined as delivery delayed by at least 48 hours, in women with singleton preterm labor
Eligibility Criteria
Inclusion Criteria:
* Age from 18 to 45 years old.
* Singleton Pregnancy
* Gestational age between 24 and 34 weeks, confirmed by last menstrual period and/or first-trimester ultrasound.
* Diagnosis of preterm labor, defined as Regular uterine contractions (≥4 in 20 minutes recorded in CTG) with a documented change in cervical dilation (e.g., from\4cm, effacement\>80%)).
* Evidence of chorioamnionitis or intrauterine infection.
* Preterm premature rupture of membranes (PPROM).
* Maternal medical disorders contraindicating tocolysis, such as severe preeclampsia, significant cardiac disease, or uncontrolled diabetes mellitus.
* Contraindications to continuation of pregnancy, including placental abruption or placenta previa with bleeding.
* Vaginal bleeding of unknown origin" as a specific exclusion criterion, as it may indicate abruption or other pathologies.
Source: ClinicalTrials.gov (NCT07696858). StuddyBuddy aggregates publicly available trial information.