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Not Yet Recruiting NCT07696858

Short-Term Tocolysis in Preterm Labor

Conditions: Preterm Labor

Sex: Female
Ages: 18 Years – 45 Years
Healthy volunteers: No
Enrollment: 100
Sponsor: Sohag University

Summary

The aim of this study is to identify independent prognostic factors associated with the success of short-term tocolysis, defined as delivery delayed by at least 48 hours, in women with singleton preterm labor

Eligibility Criteria

Inclusion Criteria: * Age from 18 to 45 years old. * Singleton Pregnancy * Gestational age between 24 and 34 weeks, confirmed by last menstrual period and/or first-trimester ultrasound. * Diagnosis of preterm labor, defined as Regular uterine contractions (≥4 in 20 minutes recorded in CTG) with a documented change in cervical dilation (e.g., from\4cm, effacement\>80%)). * Evidence of chorioamnionitis or intrauterine infection. * Preterm premature rupture of membranes (PPROM). * Maternal medical disorders contraindicating tocolysis, such as severe preeclampsia, significant cardiac disease, or uncontrolled diabetes mellitus. * Contraindications to continuation of pregnancy, including placental abruption or placenta previa with bleeding. * Vaginal bleeding of unknown origin" as a specific exclusion criterion, as it may indicate abruption or other pathologies.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07696858). StuddyBuddy aggregates publicly available trial information.