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NCT07697274
Hyaluronidase for Sclerodactyly in Systemic Sclerosis Trial
Conditions: Systemic Sclerosis, Sclerodactyly
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: EARLY_PHASE1
Enrollment: 10
Sponsor: Medical University of South Carolina
Location: Medical University of South Carolina Charleston South Carolina
Summary
Translational studies have demonstrated reduced hyaluronidase activity in the skin of patients with systemic sclerosis. It is thought this may contribute to the progressive fibrosis seen in this disease. Several studies have demonstrated that exogenous hyaluronidase is very effective at improving systemic sclerosis associated microstomia. Therefore, this study aims to explore hyaluronidase for systemic sclerosis associated sclerodactyly.
Eligibility Criteria
Inclusion Criteria:
* Age ≥18 and \
Source: ClinicalTrials.gov (NCT07697274). StuddyBuddy aggregates publicly available trial information.
