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Completed
NCT07702747
The Association Between the Stress Hormone Cortisol and Decision-making
Conditions: Healthy Young Adults
Sex: All
Ages: 18 Years – 35 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 116
Sponsor: Marie-France Marin
Location: Centre de recherche de l'Institut universitaire en santé mentale de Montréal Montreal Quebec
Summary
The goal of this study is to learn how acute psychosocial stress influences decision-making in healthy young adults. It will also examine whether cortisol reactivity, a biological stress response, changes the influence of physiological emotional signals on decision-making (i.e., the gut feeling indicating risks).
The main questions it aims to answer are:
1. Does exposure to an acute psychosocial stressor affect the development of physiological emotional signals during decision-making?
2. Does cortisol reactivity moderate the relationship between physiological emotional signals and decision-making?
3. Are there sex differences in these relationships?
Researchers will compare participants exposed to a standardized psychosocial stress procedure, with participants exposed to a non-stressful control condition.
Participants will:
1. Be randomly assigned to either a psychosocial stress condition or a control condition.
2. Complete a gambling decision-making task following the experimental manipulation.
3. Provide multiple saliva samples and subjective stress ratings throughout the session to assess stress reactivity.
4. Undergo continuous electrodermal activity recording during the decision-making task to measure physiological emotional signals.
Eligibility Criteria
Inclusion Criteria:
* Adult aged 18-35 years old.
Exclusion Criteria:
* Current or past psychiatric/neurodevelopmental disorders
* Physical illness
* Medication use (except hormonal contraception)
* Alcohol consumption exceeding Health Canada guidelines (\>10 drinks/week for women, \>15 for men)
* Smoking more than 7 cigarettes/day.
Source: ClinicalTrials.gov (NCT07702747). StuddyBuddy aggregates publicly available trial information.