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Not Yet Recruiting NCT07705763

Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy

Conditions: Refraction Error, Photorefractive Keratectomy

Sex: All
Ages: 21 Years – 40 Years
Healthy volunteers: No
Phase: NA
Enrollment: 60
Sponsor: Madina Teaching Hospital Faisalabad

Location: Madina Teaching Hospital Faisalabad Faisalābad Punjab Province

Summary

Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern, particularly during the first few days following surgery. This pain is primarily related to corneal epithelial removal, exposure of subepithelial nerve endings, and the subsequent inflammatory response. Effective pain management is therefore essential to enhance patient comfort, improve compliance with postoperative care, and increase overall surgical satisfaction. Therefore we will compare postoperative pain levels in patients undergoing PRK using ketorolac tromethamine 0.5%-soaked bandage contact lenses versus non-medicated bandage contact lenses.

Eligibility Criteria

Inclusion Criteria: * Participants selected to undergo photorefractive keratectomy for correction of refractive error after complete workup. * Participants willing to participate in the study after detailed explanation of the research purpose. Exclusion Criteria: * Known hypersensitivity to NSAIDs or ketorolac. * Presence of any systemic diseases affecting wound healing.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07705763). StuddyBuddy aggregates publicly available trial information.