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NCT07706335
Insulin Resistance and Its Association With no Reflow Phenomenon After Primary PCI in Type II Diabetic STEMI Patients.
Conditions: STEMI, No-Reflow Phenomenon, Diabetic Patient
Sex: All
Ages: 18 Years – 100 Years
Healthy volunteers: Yes
Enrollment: 100
Sponsor: Assiut University
Summary
To investigate the relationship between the TyG index, coronary lesion complexity assessed by the SYNTAX score, and the development of the no-reflow phenomenon in STEMI patients with T2DM.
Eligibility Criteria
Inclusion Criteria:
1. Age ≥ 18 years
2. Type 2 Diabetes Mellitus patients .
3. Undergoing PCI for STEMI.
4. Written informed consent obtained.
Exclusion Criteria:
* 1\. Individuals with a previous history of myocardial infarction (MI) or decompensated heart failure.
2\. Individuals with Cardiogenic shock. 3. Individuals with a history of PCI or coronary artery bypass grafting (CABG). 4.Previous familial mixed dyslipidemia / Hypertriglycerideemia (Homozygous or heterozygous).
5.Patients with significant hepatic impairment (transaminase levels ≥ 2x normal value).
6.Patients with renal impairment (GFR \< 60 mL/min/1.73 m²). 7.Active infection or inflammatory disease. 8.Known autoimmune disease. 9.Malignancy. 10. Type 1 Diabetes Mellitus patients.
Source: ClinicalTrials.gov (NCT07706335). StuddyBuddy aggregates publicly available trial information.
