Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients

Conditions: Osteoporosis, Dental Caries, Biomarkers, Matrix Metalloproteinase 8

Sex: All

Ages: 45 Years – 75 Years

Healthy volunteers: Yes

Enrollment: 50

Sponsor: Afyonkarahisar Health Sciences University

Summary

This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.

Eligibility Criteria

Inclusion Criteria: * Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia Exclusion Criteria: * Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07709247). StuddyBuddy aggregates publicly available trial information.