Closed Incision NPWT to Prevent Wound Complications Post-ECMO

Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden. Closed incision negative pressure wound therapy (NPWT) may improve wound healing by reducing fluid accumulation and supporting the incision. This study evaluates whether prophylactic NPWT reduces wound complications compared to standard wound care following ECMO decannulation.

Inclusion Criteria: * Patient is aged 18 years or older * Is currently receiving ECMO therapy and is eligible for weaning from the device * The patient must have at least one cannula inserted at the groin site * (Proxy) informed consent Exclusion Criteria: * Duration ECMO run \< 24 hours * Expected death within 24 hours after decannulation * Extracorporeal carbon dioxide removal (ECCO2R) using low blood flow devices or pumpless devices (i.e., MINILUNG ®, PrismaLung+) * Wound closure is not possible after decannulation. * Presence of drain in the wound site * Participants who are not proficient in Dutch or English, or whose legal representative is not proficient, if applicable