Sustained Release Oral Formulation For Treatment Of Parkinsons Disease

Sex: All

Ages: 18 Years – 65 Years

Healthy volunteers: Yes

Phase: PHASE1, PHASE2

Enrollment: 32

Sponsor: University of Minnesota

Summary

LD/CD (medications to treat Parkinson's disease) will be delivered using an assembly of nested sachets made of permeable material. The assembly is placed in the oral/buccal cavity (between cheek and gum of lower jaw) and delivers continuous release of CD and LD for both transmucosal and gastrointestinal absorption. The combination of CD/LD in the inner sachet varies from that in the outer sachet. This allows for sequential release of CD and then LD to mimic a CD pretreatment method which is known to increase LD absorption and prolong its half-life.

Eligibility Criteria

Inclusion Criteria: * Adult healthy male or female * Age 18 to 65 years * Willingness and ability to complete study procedures Exclusion Criteria: * medical conditions that require taking medications regularly.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07709741). StuddyBuddy aggregates publicly available trial information.