Biomarkers for Endometriosis

Endometriosis is a condition in which tissue similar to the lining of the uterus grows outside the uterus, often causing pain and infertility. Currently, endometriosis can only be definitively diagnosed through invasive procedures like laparoscopy and biopsy. The purpose of this study is to investigate whether the proteins Synuclein Gamma (SNCG) and B-Cell Lymphoma 6 (BCL6), measurable in blood and menstrual fluid, can serve as non-invasive biomarkers to diagnose or monitor endometriosis.

Inclusion Criteria for Endometriosis Group: * Women of reproductive age group (18Y-45Y). * Women with active endometriosis diagnosed by ultrasound/MRI/laparoscopy. Exclusion Criteria for Endometriosis Group: * Women \45Y. * Women with endometriosis during stimulation with gonadotropins. * Current or prior history of uterine, ovarian, colon, pancreatic, breast or any other type of cancer. * Any prior history of chronic illness. * Pregnant women. Inclusion Criteria for Control Group: * Women of reproductive age group (18Y-45Y). * Women without endometriosis and any other gynaecological problem. Exclusion Criteria for Endometriosis Group: * Women \45Y * Prior history of any disease including cancer or chronic illness. * Pregnant women.