Low Dose Radiotherapy for Osteoarthritis

This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.

Inclusion Criteria: * 18 years or older * Diagnosis of OA \>3 months in hips, knees, hands, shoulders, ankles or elbows. * Refractory to standard of care therapies for OA or those who are being considered for more aggressive interventional treatment such as joint replacement, but more conservative treatment is desired. * Provision of signed and dated informed consent. Exclusion Criteria: * Unable to reasonably complete study instruments.