Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow

The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing different acute surgical diseases (ASD). The research is based on real-world data (RWD) from a large multidisciplinary hospital repurposed as a COVID-19 center. The study analyze the mutual impact of these two acute conditions on patient outcomes, develop prognostic models for in-hospital mortality, and evaluate changes in surgical approaches during the pandemic.

Inclusion Criteria: * Age 18 years or older. * Hospitalization at the MMCC "Kommunarka". * A confirmed diagnosis of COVID-19 (based on current clinical guidelines). * Presence of one or more any acute surgical diseases (ASD) considered competing with COVID-19 or as a complication of COVID-19/its treatment, as per the discharge summary. * For specific sub-studies: Patients with acute surgical diseases of the abdominal organs. * For specific sub-studies: Patients with clinically significant spontaneous soft tissue hematomas or pneumomediastinum or other acute surgical diseases. Exclusion Criteria: * Patients for whom a diagnosis of COVID-19 was not established according to the discharge summary. * Patients for whom none of the studied acute surgical diseases were established according to the discharge summary. * Patients who underwent elective surgeries and developed COVID-19 in the postoperative period. * Patients operated on in another hospital and transferred with suspected COVID-19 (if not confirmed).