Does Erectile Dysfonction Allow to Evaluate Subendocardial Viability Among Treated Patients With Hypertension ?

Erectile dysfunction (ED) is associated with subclinical atherosclerosis and may precede clinically apparent coronary artery disease by two to five years. It may therefore serve as an early warning sign of cardiovascular disease and help identify patients who could benefit from intensified cardiovascular risk-factor management. The subendocardial viability ratio (SEVR), also known as the Buckberg index, is obtained noninvasively from radial artery applanation tonometry. SEVR reflects the balance between myocardial oxygen supply and demand and has been associated with coronary flow reserve in patients with hypertension. The DEVISE study will compare SEVR between treated men with hypertension who have ED with those who do not. The study will also examine the associations between ED severity and arterial stiffness, central hemodynamics, exercise capacity, left ventricular mass, coronary artery calcium, high-sensitivity C-reactive protein, cardiovascular risk, and quality of life. The question addressed in our study is whether an alteration in subendocardial viability represents subclinical coronary disease associated with ED.

Inclusion Criteria: * Male participant aged 18 years or older. * Confirmed diagnosis of hypertension. * Receiving pharmacological antihypertensive treatment. * Consecutively admitted to the hypertension day-hospital unit for assessment of hypertension-mediated organ damage. * No history of cardiovascular disease, particularly coronary artery disease, and asymptomatic for coronary artery disease. * Affiliated with a French social security scheme. * Having received the study information and not expressed opposition to participating. Exclusion Criteria: * Permanent atrial fibrillation * Recurrent cardiac arrhythmias * Not affiliated with a French social security scheme * Opposition to participation