Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome

This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome compared with patients without pseudoexfoliation. Corneal hysteresis (CH), corneal resistance factor (CRF) and corneal astigmatism will be measured before surgery and at postoperative follow-up visits. The relationship between changes in corneal biomechanics and surgically induced astigmatism will be analyzed.

Inclusion Criteria: * Adults aged 50-85 years * Age-related cataract scheduled for standard phacoemulsification cataract surgery with intraocular lens implantation * Presence of pseudoexfoliation syndrome (PEX group) or absence of pseudoexfoliation syndrome (control group) * Ability to provide written informed consent * Willingness to attend all scheduled postoperative follow-up visits Exclusion Criteria: * Previous ocular surgery in the study eye * Corneal diseases or abnormalities that may affect corneal biomechanical measurements or keratometry * Glaucoma and ocular hypertension * Ocular trauma or active ocular inflammation