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NCT07722598
Memory Enhancement in Aging With Closed-Loop tACS
Conditions: Aging, Noninvasive Brain Stimulation, Memory
Sex: All
Ages: 65 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 160
Sponsor: Boston University Charles River Campus
Summary
This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen memory-supporting networks.
Eligibility Criteria
Inclusion Criteria:
* 65 years of age or older
* normal or corrected-to-normal vision
* color vision
Exclusion Criteria:
* pregnant
* metal implants in head
* implanted electronic devices
* history of neurological problems or head injury
* skin sensitivity
* claustrophobia
* dementia (normal Montreal Cognitive Assessment \> 25)
* depression (normal Geriatric Depression Scale \< 10)
* history of psychosis
* cognitive deficits (MoCA\>25)
* any psychoactive medication
Source: ClinicalTrials.gov (NCT07722598). StuddyBuddy aggregates publicly available trial information.