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NCT07724145
Association Between Female Hormonal Profile and Wound Healing
Conditions: Wound Healing, Wound Healing Complication, Estradiol
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 84
Sponsor: University Hospital, Geneva
Location: University Hospital of Geneva Geneva
Summary
The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are:
1. Does wound healing differ depending on whether the operation takes place before or after ovulation in the menstrual cycle?
2. Does estradiol have a positive effect on wound healing?
Participants with mammary hypertrophy will undergo reduction mammaplasty, and the investigators will measure their hormonal profile (LH, FSH, and estradiol) on the day of surgery.
Eligibility Criteria
Inclusion Criteria:
* Symptomatic breast hypertrophy
* Premenopausal
Exclusion Criteria:
* Previous breast reduction surgery
* Menopausal status
* Oral contraceptives
* Corticosteroid therapy
* History of breast cancer
* Active smoking and use of nicotine substitution products
Source: ClinicalTrials.gov (NCT07724145). StuddyBuddy aggregates publicly available trial information.
