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NCT07724483
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
Conditions: Lipedema
Sex: Female
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Enrollment: 90
Sponsor: Marmara University
Location: Marmara University School of Medicine Pendik Research and Training Hospital Istanbul Pendik
Summary
This study aims to investigate the relationship between lower extremity muscle/tendon characteristics and walking/balance functions in women with lipedema. Lipedema is a condition characterized by abnormal fat accumulation that can lead to walking difficulties and joint problems. We will use ultrasonography to measure muscle thickness and tendon structures, and a pedobarography system to analyze foot pressure distribution during standing and walking. By comparing 45 patients with 45 healthy volunteers, we aim to identify the musculoskeletal causes of gait disorders in lipedema to help develop better prevention and treatment strategies
Eligibility Criteria
Inclusion Criteria:
* Female patients aged 18-65 years and diagnosed with lipedema by a clinician.
* To agree to participate in the research.
Exclusion Criteria:
* Positivity of Stemmer's sign (inability to compress the skin between the proximal phalanges of the 2nd and 3rd fingers)
* Patients with Heart Failure
* Patients with Chronic Kidney Disease
* Motor neuron diseases or myositis
* Diseases causing myositis
* Patients diagnosed with polyneuropathy
* Patients with motor-involved L3, L4, L5, or S1 radiculopathy
* Those unable to ambulate independently
* Those who cannot tolerate the assessments
* Pregnant women
* Congenital or traumatic lower extremity disorders (e.g., developmental hip dysplasia, previous lower extremity fractures with orthopaedic implants).
Source: ClinicalTrials.gov (NCT07724483). StuddyBuddy aggregates publicly available trial information.