← Back to all trials
Active Not Recruiting
NCT07725107
Topical Oxygen Therapy for BRONJ
Conditions: Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen, Topical Administration, Wound Healing
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 36
Sponsor: Mansoura University
Location: Faculty of Dentistry Mansoura University Al Mansurah
Summary
A randomized clinical trial comparing Blue®m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
Eligibility Criteria
Inclusion Criteria:
* Patient Age: ≥18 years.
* Patients diagnosed with BRONJ/MRONJ Stage 1-3 (AAOMS criteria).(25)
* History of antiresorptive or antiangiogenic drug use.
* Patients willing to participate in the study's follow-up intervals and to provide informed consent.
Exclusion Criteria:
* Previous radiotherapy to head and neck
* Uncontrolled systemic disease (e.g., uncontrolled diabetes)
* Pregnancy or lactation
* Known allergy to Blue®m components
* Uncooperative patients.
Source: ClinicalTrials.gov (NCT07725107). StuddyBuddy aggregates publicly available trial information.
