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Recruiting
NCT07726511
Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
Conditions: Face
Sex: All
Ages: 20 Years – 40 Years
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: UConn Health
Location: UConn Health Farmington Connecticut
Summary
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults. Twenty participants aged 20-40 years will undergo three-dimensional facial imaging (3dMD) at baseline (T0), after the 4-week chewing intervention (T1), and following a 4-5-week washout period (T2). Changes in facial soft-tissue morphology will be assessed using three-dimensional surface analysis, including heatmaps, regional surface displacement, and morphometric measurements. Secondary outcomes include self-reported muscle fatigue, soreness, adherence, and temporomandibular disorder (TMD) symptoms.
Eligibility Criteria
Inclusion Criteria:
* Healthy, non-smoking adults.
* Age 20 to 40 years.
* Presence of a full dentition from central incisor to first molar in all four quadrants, excluding second molars.
* Stable occlusion with no ongoing orthodontic treatment or myofunctional therapy.
* Ability and willingness to comply with the prescribed hard-gum chewing regimen for 4 weeks and attend all study visits.
* Ability to provide written informed consent.
Exclusion Criteria:
* Age younger than 20 years or older than 40 years.
* Evident facial asymmetry from a frontal view.
* Signs or symptoms of temporomandibular disorders (TMD) according to the Diagnostic Criteria for TMD (DC/TMD).
* Less than the normal range of condylar motion during maximum opening and closing.
* Parafunctional habits such as bruxism with pain, clenching, or habitual gum chewing for more than 1 hour per day.
* History of major craniofacial trauma, orthognathic surgery, or congenital craniofacial anomalies.
* Ongoing orthodontic treatment or recent removal of fixed appliances (\
Source: ClinicalTrials.gov (NCT07726511). StuddyBuddy aggregates publicly available trial information.