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Not Yet Recruiting NCT07729072

The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers

Conditions: Healthy Adult Participants, Exercise Training, Neuromuscular Adaptations, Nutritional Intervention

Sex: All
Ages: 18 Years – 45 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 60
Sponsor: University of Lausanne

Location: Bâtiment Synathlon, quartier UNIL-Centre Lausanne

Summary

The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.

Eligibility Criteria

Inclusion Criteria: 1. Being between 18 and 45 years old 2. Being healthy (assessed through the PAR-Q questionnaire). 3. Being physically active, but not involved in any structured training program 4. Being available for the study period. Exclusion Criteria: 1. If a participant answers positively to any YES/NO question in the PAR-Q health questionnaire. For questions requiring a precision, any positive answer will be reviewed by a medical doctor, who will determine the inclusion/exclusion of the participant. 2. Having allergy to xylocaine 3. Being pregnant.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07729072). StuddyBuddy aggregates publicly available trial information.