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NCT07729072
The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers
Conditions: Healthy Adult Participants, Exercise Training, Neuromuscular Adaptations, Nutritional Intervention
Sex: All
Ages: 18 Years – 45 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 60
Sponsor: University of Lausanne
Location: Bâtiment Synathlon, quartier UNIL-Centre Lausanne
Summary
The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.
Eligibility Criteria
Inclusion Criteria:
1. Being between 18 and 45 years old
2. Being healthy (assessed through the PAR-Q questionnaire).
3. Being physically active, but not involved in any structured training program
4. Being available for the study period.
Exclusion Criteria:
1. If a participant answers positively to any YES/NO question in the PAR-Q health questionnaire. For questions requiring a precision, any positive answer will be reviewed by a medical doctor, who will determine the inclusion/exclusion of the participant.
2. Having allergy to xylocaine
3. Being pregnant.
Source: ClinicalTrials.gov (NCT07729072). StuddyBuddy aggregates publicly available trial information.