Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers

Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early stage. Therefore, early detection of carious lesions is essential to implement preventive and minimally invasive treatment strategies before irreversible tooth destruction occurs.

Inclusion Criteria: \- Presence of at least one suspected initial enamel carious lesion. Exclusion Criteria: * Cavitated carious lesions * Previous restorative treatment on the examined tooth * Antibiotic therapy during the previous month, * Systemic diseases affecting salivary secretion * Xerostomia or salivary gland disorders