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NCT07734428
Inflammation and Diabetes: Evaluating Antioxidant Levels
Conditions: Diabete Mellitus, Diabete Type 2, Inflamation, Systemic Inflammation, Dietary Inflammatory Index (DII), Systemic Inflammation Markers
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Enrollment: 180
Sponsor: Istanbul Bilgi University
Location: Gaziosmanpasa Training and Research Hospital Istanbul
Summary
The goal of this observational, cross-sectional study is to evaluate the relationships between dietary total antioxidant capacity, systemic inflammatory response markers, and nutritional parameters in adult patients with Type 2 Diabetes (T2DM). Participants will be classified into controlled (HbA1c \< %7) and uncontrolled (HbA1c ≥ %7) diabetes groups based on their glycemic control. The main questions it aims to answer are: Does dietary antioxidant capacity affect systemic inflammation levels and metabolic parameters? Is there a relationship between nutritional risk status and inflammatory response in T2DM patients?
Eligibility Criteria
Inclusion Criteria:
* Adults aged 18 and older diagnosed with Type 2 Diabetes.
* Individuals whose biochemical analyses have been performed by a physician within the last 1 month.
* Individuals willing to participate voluntarily.
Exclusion Criteria:
* Missing required laboratory data in the last 1 month.
* Presence of acute infection or inflammatory disease.
* Advanced kidney or liver failure.
* Active malignancy or receiving chemotherapy/radiotherapy.
* Pregnant and lactating women.
* Use of antioxidant/vitamin-mineral supplements.
* Receiving special diet therapies (e.g., time-restricted, ketogenic, or elimination diet).
* Advanced cognitive impairment or communication difficulties.
Source: ClinicalTrials.gov (NCT07734428). StuddyBuddy aggregates publicly available trial information.