Robotic Systems Evaluation for Peripheral Pulmonary Lesions (RISE Trial)

This is an investigator-initiated cluster randomized control trial. The primary objective is to compare the diagnostic yield of two Food and Drug Administration (FDA) cleared national robotic assisted bronchoscopy platforms - the Monarch™ Platform and the ION™ Endoluminal System - in participants undergoing bronchoscopy to evaluate peripheral pulmonary lesions (PPLs). Participants will undergo their scheduled robotic assisted bronchoscopy (RAB) using one of these platforms.

Inclusion Criteria: * Age ≥ 18 years at the time of bronchoscopy. * Scheduled to undergo navigational bronchoscopy (either ION™ or Monarch™) for the evaluation of a pulmonary lesion at University Hospitals Cleveland Medical Center (UHCMC). * Able and willing to provide written informed consent. Exclusion Criteria: * Enrolled in another clinical trial that requires the use of a specific navigational/robotic bronchoscopy platform. * Enrolled in another bronchoscopy-related clinical trial. * Participant or legally authorized representative declines participation.