Clinical, Radiographic and Volumetric Evaluation of the Entire Papilla Preservation Technique With and Without Connective Tissue Graft in the Treatment of Periodontal Intraosseous Defects.

This study is to assess the impact of implementing subepithelial connective tissue graft (SCTG) in the treatment of periodontal intrabony defects with Entire Papilla Preservation Technique (EPPT) on the clinical and radiographic results after 6 and 12 months.

Inclusion Criteria: * Age ≥ 18 years, * Good compliance and good oral hygiene * Systemically healthy * Isolated two intrabony defects of more than 3 mm depth, combined with more than 6 mm probing depth and attachment loss (stage III/IV periodontitis) and an intrabony radiographic defect depth (DD) ≥ 3 mm, as evaluated on a digital periapical radiograph * The associated tooth should either maintain normal pulp vitality or should have undergone root canal therapy for at least 6 months before. Exclusion Criteria: * Full-mouth plaque score ≥ 20% (O'Leary et al 1972) * Full-mouth bleeding score ≥ 20% (Cortellini et al 1995) * Smoking * Systemic diseases that would adversely influence wound healing * Medications interfering with post-operative wound healing * Pregnant and lactating females * Previous periodontal surgery in the examined area * III-degree mobility * Furcation involvement * Pulpal pathology or inadequate endodontic treatment