Speed of Processing Training to Improve Cognitive Functioning and Driving Performance in Head and Neck Cancer Survivors

The goal of the study is to understand how well cognitive training improves reaction time in people with head and neck cancer (HNC). Aim 1. Evaluate the preliminary clinical effectiveness of a 10-week home- and video game-based SOPT on cognitive functioning and driving performance in HNC survivors. This study will include completing five questionnaires and simulated driving in a simulator at two different times, 10 weeks of participating in 2 sessions per week of video-game cognitive training at home and being interviewed once at the end of the 10-week training.

Inclusion Criteria: * confirmed HNC diagnosis * aged ≥ 18 years of all racial, ethnic, and sex/gender categories * ≥ 6 months post radiation or chemoradiation * self-reported CRCI, defined as a score of ≥ 60 in the FACT-Cog Perceived Cognitive Impairment subscale * thyroid-stimulating hormone levels within normal limits * visual acuity of at least 20/40 using a Snellen eye chart * functional peripheral vision as indicated by the confrontation field test * functional hearing sufficient to engage in daily conversation in English for ≥ 15 minutes * intact lower extremity function (Rapid Pace Walk test ≤ 9 sec) * stable home internet * sufficient English proficiency to read and understand informed consent materials Exclusion Criteria: * significant neurologic or psychiatric comorbidities, including psychotic disorders, bipolar disorders, Alzheimer's disease or related dementias, developmental disorders, seizure disorders, vestibular disorders, prior brain tumor or brain surgery, or poorly controlled metabolic disease * current use of antipsychotic or mood-stabilizing medications due to potential effects on driving performance * anticipated life expectancy of \< 6 months based on physician prognosis.