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Not Yet Recruiting NCT07741409

Povidone Iodine for Caries Prevention

Conditions: Dental Caries

Sex: All
Ages: 1 Year – 3 Years
Healthy volunteers: Yes
Phase: PHASE3
Enrollment: 174
Sponsor: Jeffrey A. Banas

Location: University of Iowa College of Dentistry Iowa City Iowa

Summary

The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1. How will home use of Povidone Iodine, as an adjunct treatment to standard dental care, reduce the incidence of tooth decay? 2. How will home use of Povidone Iodine reduce the mouth germs responsible for tooth decay? 3. If Povidone Iodine use is accompanied by probiotic use, will its effectiveness be even better than Povidone Iodine alone? Participants will: 1. Provide a plaque sample at the beginning of the study. 2. Swab their children's teeth once a week for one month and then monthly thereafter. Some participants may be asked to use probiotic drops nightly after brushing their teeth. 3. Keep a record of compliance. 4. Return every 6 months for a dental exam and to provide a plaque sample. Keep a diary of their symptoms and the number of times they use a rescue inhaler

Eligibility Criteria

Inclusion Criteria * 1 to 3 years of age * No plans to relocate in the next 12 months Exclusion Criteria * Thyroid condition * Antibiotic usage in the prior 3 months

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07741409). StuddyBuddy aggregates publicly available trial information.