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NCT07748468
Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
Conditions: Overweight , Obesity, Antioxidant Status
Sex: All
Ages: 21 Years – 70 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 83
Sponsor: National University of Singapore
Location: NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117550 Singapore
Summary
This study aims to evaluate the effects of antioxidant-rich supplementation on skin carotenoid status, antioxidant status, and cardiometabolic health in overweight and obese individuals. The study may provide additional scientific evidence to support the further refinement of current dietary and nutritional recommendations.
Eligibility Criteria
Inclusion Criteria:
* Able to give informed consent (AMT score ≥ 8 for older adults \[65-70 years old\])
* Adults 21-70 years old
* English-literate
* Have venous access sufficient to allow for blood sampling as per the protocol
* No drastic change of diet for the past 1 year
* If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 3 years prior to starting the study
Exclusion Criteria:
* Weight change \> 3kg in the past 3 months
* Exercising vigorously over the past 3 months
* Taking medications or dietary supplements which may impact eye/skin health
* Taking lipid-lowering and blood pressure controlling medications less than 3 years
* Smoking
* Drinking more than 2 alcoholic drinks per day
* Pregnant, lactating, or planning pregnancy in the next 6 months
Source: ClinicalTrials.gov (NCT07748468). StuddyBuddy aggregates publicly available trial information.