Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols

The primary purpose of this study is to evaluate the effects of CellCore protocols on environmental toxicant biomarkers among adult patients with high baseline toxicant levels. Patients will be allocated to one of two CellCore protocols (Foundational Protocol or BioToxin Binder/Drainage Activator) based on overall physical health, mental health, and fatigue levels at baseline. A prospective, practitioner-led, open-label, single-arm intervention with the CellCore protocols will be conducted to measure pre- and post-intervention changes in urinary environmental toxicant biomarkers and validated, patient-reported health outcomes.

Inclusion Criteria: 1. Adult between 25 and 65 years of age 2. Documented elevated urinary environmental toxicant levels above the 75th percentile of at least 5 toxins on baseline environmental toxin test 3. PROMIS - Global Health - Physical Health t-scores \< 42.4 for Foundational Protocol (otherwise BioToxin Binder/Drainage Activator Protocol) 4. Currently receiving care from a qualified, participating practitioner 5. Lives in the United States 6. Ability to speak and read English 7. Willing and able to follow the assigned CellCore protocols and complete all required testing and questionnaires 8. Willing and able to provide informed consent Exclusion Criteria: 1. Currently undergoing active chelation therapy 2. Participation in a structured detoxification program within the prior 60 days, including use of activated charcoal, bentonite/zeolite clay, chlorella, cholestyramine 3. Ongoing occupational toxic exposure (e.g., working on golf course, dry cleaning facility) that cannot be reduced or controlled during the study period 4. Pregnancy or lactation, or planning pregnancy during the study period 5. Major comorbid medical condition requiring complex specialty management that, in the practitioners' clinical judgment, would interfere with safe study participation 6. Anticipated initiation of additional detoxification products, major dietary changes, or other significant co-interventions during the study period 7. Unable or unwilling to provide informed consent