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Active Not Recruiting
NCT07757360
Administration of Oral Probiotic Streptococcus Salivarius K12
Conditions: Oral Health
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 12
Sponsor: University of Zurich
Location: Center for Dental Medicine Zurich Canton of Zurich
Summary
The clinical trial is investigating the oral administration of probiotic Streptococcus salivarius K12 in the form of lozenges in healthy adults.
The main outcome measures are:
* Potential for Streptococcus salivarius K12 to colonise the oral cavity
* Effect on other bacteria and Candida albicans in the oral cavity
* Possible anti-inflammatory effect
Participants will:
* Take one lozenge containing Streptococcus salivarius K12 daily for 4 weeks
* Attend 3 dental check-ups (before starting the probiotic treatment, and after 4 and 8 weeks)
* Collect their own saliva samples in accordance with a sampling schedule
Eligibility Criteria
Inclusion Criteria:
* Healthy volunteers
* Adults (\> 18 years)
* no caries or periodontal disease
Exclusion Criteria:
Within the last 4 weeks before the trial, intake of...
* anti-inflammatory drugs
* antimicrobial substances
* probiotics
Source: ClinicalTrials.gov (NCT07757360). StuddyBuddy aggregates publicly available trial information.
