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NCT07766356
Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia
Conditions: Stroke
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: NA
Enrollment: 30
Sponsor: University Hospital, Toulouse
Location: Service de Médecine Physique et de Réadaptation Hôpital Raymonde Fournet Purpan Toulouse
Summary
In France, stroke affects 150,000 people annually and is the leading cause of acquired disability in adults; 10-12% of patients exhibit mild post-stroke aphasia, a condition defined by language difficulties.
Few studies describe mild post-stroke aphasia, and none characterize the impairment of linguistic executive control in this population; consequently, its prevalence remains unknown. To date, the role of linguistic executive control in mild aphasia remains an open question.
The aim of this project is to investigate linguistic executive control impairment in stroke survivors with mild aphasia, provide an initial estimate of its prevalence, and demonstrate its interactions with other linguistic and communicative aspects, as well as with executive and attentional functions.
Eligibility Criteria
Inclusion Criteria:
* Patient who has experienced a first ischemic stroke resulting in clinical symptoms within the last 3 months and is receiving care in the Physical Medicine and Rehabilitation department.
* Score ≤ 31 on the conversational speech observation scale of the MEC test (Montreal Protocol for the Evaluation of Communication).
* Patients with a BDAE score ≥ 3 (Boston Diagnostic Aphasia Examination - French version, Mazaux J.-M. \[1990\]); this score is the gold standard in aphasiology.
* Native French-speaking patient capable of understanding oral or written instructions.
Exclusion Criteria:
* Patients exhibiting behavior or a clinical condition incompatible with test administration, as assessed by the clinician.
* Known major visual, auditory, or motor impairments incompatible with test performance.
* Known neurodegenerative and/or neurodevelopmental disorders.
* Known social cognition disorders (e.g., ASD).
Source: ClinicalTrials.gov (NCT07766356). StuddyBuddy aggregates publicly available trial information.