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Not Yet Recruiting NCT07768917

Training on Systemic and Organ Spec. PM in PC

Conditions: Prostate Cancer

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: Massachusetts General Hospital

Location: Massachusetts General Hospital Boston Massachusetts

Summary

This research is being done to assess the impact of a supervised and structured strength and conditioning program on cardiac remodeling in participants with prostate cancer undergoing treatment with external beam radiation therapy and at least 6 months of Gonadotropin-releasing hormone (GnRH) therapy.

Eligibility Criteria

Inclusion Criteria: * Have histologically or cytologically confirmed adenocarcinoma of the prostate * Have not received GnRH agonist or antagonist within the last 12 months * Planned for initiation of a GnRH agonist or antagonist or bilateral orchiectomy with an intended treatment duration of ≥ 6 months * Planned for initiation of radiation therapy to the prostate. * ECOG performance status of 0 or 1 * Ability to understand and the willingness to sign a written informed consent document * Baseline serum total testosterone level \> 230 ng/dL (the accepted threshold for testosterone supplementation) * Speak English -\>18 years of age Exclusion Criteria: * Has a known medical condition that makes the subject unable to participate in exercise testing (e.g. unrevascularized coronary artery disease, moderate/severe osteoarthritis, prior stroke, or other conditions) * Receiving or planned to receive other cancer therapy not included in Eligibility Criterion 3.1.3 (other than an antiandrogen during the first month of therapy) * The following populations will not be considered for inclusion on this trial.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07768917). StuddyBuddy aggregates publicly available trial information.