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Not Yet Recruiting
NCT07768917
Training on Systemic and Organ Spec. PM in PC
Conditions: Prostate Cancer
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: Massachusetts General Hospital
Location: Massachusetts General Hospital Boston Massachusetts
Summary
This research is being done to assess the impact of a supervised and structured strength and conditioning program on cardiac remodeling in participants with prostate cancer undergoing treatment with external beam radiation therapy and at least 6 months of Gonadotropin-releasing hormone (GnRH) therapy.
Eligibility Criteria
Inclusion Criteria:
* Have histologically or cytologically confirmed adenocarcinoma of the prostate
* Have not received GnRH agonist or antagonist within the last 12 months
* Planned for initiation of a GnRH agonist or antagonist or bilateral orchiectomy with an intended treatment duration of ≥ 6 months
* Planned for initiation of radiation therapy to the prostate.
* ECOG performance status of 0 or 1
* Ability to understand and the willingness to sign a written informed consent document
* Baseline serum total testosterone level \> 230 ng/dL (the accepted threshold for testosterone supplementation)
* Speak English -\>18 years of age
Exclusion Criteria:
* Has a known medical condition that makes the subject unable to participate in exercise testing (e.g. unrevascularized coronary artery disease, moderate/severe osteoarthritis, prior stroke, or other conditions)
* Receiving or planned to receive other cancer therapy not included in Eligibility Criterion 3.1.3 (other than an antiandrogen during the first month of therapy)
* The following populations will not be considered for inclusion on this trial.
Source: ClinicalTrials.gov (NCT07768917). StuddyBuddy aggregates publicly available trial information.