Join us at Health Research Day — June 6th at Canton Waterfront Park, Baltimore!   Learn More →
← Back to all trials
Not Yet Recruiting NCT07784127

Whole Gut Motility Abnormalities Following GLP-1 Receptor Agonist (GLP-1RA) Initiation

Conditions: Diabetes

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: The Cleveland Clinic

Location: Cleveland Clinic Cleveland Ohio

Summary

Participants will undergo evaluation with the Atmo capsule at two time points: at baseline before starting the GLP-1RA or dual agonist therapy and after the subject has been taking their GLP-1RA or dual agonist therapy for 3 months. The total expected time for patient participation is up to 4 months from the time they start their GLP-1RA or dual agonist therapy.

Eligibility Criteria

Inclusion Criteria: * Adult patients (18 years or older) * Initiating GLP-1RA or GLP-1RA/GIP (dual agonist) therapy, or off GLP-1RA or GLP1-RA/GIP therapy for greater than 3 months for the treatment of type 2 diabetes with or without obesity (BMI \> 30 kg/m2) at the time of the baseline visit * Stable glucose control (HbA1c ≤ 9%) within 6 months of the baseline visit * Normal TSH within 6 months of baseline visit Exclusion Criteria: * Current use of opiates, marijuana, anticholinergics, or pro-motility medications. Can be included if there is no utilization for at least 1 month. * Use of antibiotics within the past 2 weeks * History of gastric or bowel surgery * Known or suspected history or active intestinal obstruction or stricture * Pregnancy * Patients for whom English is not their primary language will be excluded. * Cognitively impaired persons or other vulnerable populations who are unable to provide informed consent will be excluded.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07784127). StuddyBuddy aggregates publicly available trial information.