CEST for Prostate Biopsy

Sex: Male

Ages: 18 Years – N/A

Healthy volunteers: No

Phase: NA

Enrollment: 20

Sponsor: Sunnybrook Health Sciences Centre

Summary

Samples of prostate tissue acquired by biopsy to determine whether there is cancer will sometimes not find cancer that is present. Conventionally, magnetic resonance imaging (MRI) is used to identify 12 areas to biopsy. We will use an advanced MRI method called magnetization transfer (MT) and chemical exchange saturation transfer (CEST) imaging to suggest two additional biopsy location. Our objectives are to determine 1) whether MT/CEST MRI can aid in the detection prostate cancer and 2) whether MT/CEST MRI can aid conventional MRI in risk stratification and to decide whether targeted prostate biopsy is justified.

Eligibility Criteria

Inclusion Criteria: * PI-RADS category 3 prostate cancer with upcoming targeted biopsy Exclusion Criteria: * Contraindications to MRI * Prior radiotherapy * Prior chemotherapy * Prior prostate biopsy

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07785024). StuddyBuddy aggregates publicly available trial information.