← Back to all trials
Not Yet Recruiting
NCT07791316
Serum GDF-15 in Carpal Tunnel Syndrome
Conditions: Carpal Tunnel Syndrome
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Enrollment: 60
Sponsor: Kanuni Sultan Suleyman Training and Research Hospital
Summary
This observational study aims to evaluate serum Growth Differentiation Factor-15 (GDF-15) levels in patients with idiopathic carpal tunnel syndrome compared with asymptomatic controls. The study will also assess the associations between serum GDF-15 levels and clinical and electrophysiological characteristics of carpal tunnel syndrome.
Eligibility Criteria
Inclusion Criteria:
* Age 18-65 years.
* Written informed consent.
* For the patient group: idiopathic carpal tunnel syndrome confirmed by clinical and electrophysiological evaluation.
* For the control group: asymptomatic individuals without a previous diagnosis of carpal tunnel syndrome and without clinical signs of carpal tunnel syndrome.
Exclusion Criteria:
* Diabetes mellitus.
* Hypothyroidism.
* Rheumatoid arthritis or other inflammatory rheumatic diseases.
* Pregnancy.
* Cervical radiculopathy or polyneuropathy.
* Previous carpal tunnel or wrist surgery.
* History of wrist trauma or fracture.
* Corticosteroid injection into the carpal tunnel within the previous 3 months.
* Malignancy.
* Chronic kidney or liver disease.
* Active infection or autoimmune disease.
* Serious systemic conditions that may affect serum GDF-15 levels.
Source: ClinicalTrials.gov (NCT07791316). StuddyBuddy aggregates publicly available trial information.
