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Not Yet Recruiting
NCT07792941
A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called Tilrekimig in Healthy Adults When Co-Mixed With rHuPH20
Conditions: Healthy
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 12
Sponsor: Pfizer
Location: New Haven Pfizer Clinical Research Unit (NH PCRU) New Haven Connecticut
Summary
This study aims to learn how the body handles tilrekimig when given with another medicine called recombinant human hyaluronidase PH20 (rHuPH20). rHuPH20 is approved to help some medicines be taken up by the body when they are given together as an injection (shot) under the skin.
Eligibility Criteria
Inclusion Criteria:
* BMI of 16-32 kg/m2; and a total body weight \>50 kg (110 lb).
* Participants who are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures. Participants should be able to understand and sign informed consent
Exclusion Criteria:
* Evidence or history of clinically significant any medical condition
* History of HIV infection, hepatitis B, or hepatitis C; positive testing for HIV, HBsAg, HBcAb or HCVAb.
* Evidence of active, latent, or inadequately treated infection with Mycobacterium TB
* History of allergic or anaphylactic reaction with any biologic agents.
Source: ClinicalTrials.gov (NCT07792941). StuddyBuddy aggregates publicly available trial information.