Comparison of KIRA Hydrating Treatment and Jet Peel for Facial Skin Hydration

This study compared the efficacy and tolerability of two non-invasive facial treatment systems for improving skin hydration: a hydroabrasion-jet system (KIRA) and a conventional high-pressure jet system (JET PEEL). Twenty-three women aged 30-65 years underwent three treatment sessions using an intraindividual split-face design, with KIRA applied to the left side of the face and JET PEEL to the right side. Skin hydration was assessed by corneometry at baseline, 48 hours after the first treatment, and before the second and third treatments, with the measurement before the third treatment defined as the primary endpoint. Additional exploratory assessments included multispectral skin imaging, participant-reported treatment experience and preference, and a Day-21 follow-up. The study aimed to determine whether enhanced epidermal preparation using hydroabrasion combined with lower-pressure jet infusion could achieve hydration outcomes comparable to those obtained with a conventional higher-pressure jet system.

Inclusion Criteria: Female participants aged 30-65 years Fitzpatrick skin types II-III Presence of signs of facial skin aging, including one or more of the following: hyperkeratosis, hyperpigmentation, facial or age-related wrinkles, and enlarged pores Generally healthy and without contraindications to the study procedures Willing and able to provide informed consent and participate in the study procedures Exclusion Criteria: Pregnancy or breastfeeding Serious vascular disorders Pacemaker or metal implants in the treatment area Malignant skin disease Autoimmune or endocrine disease, diabetes, or AIDS Psoriasis, herpes, or other active skin disease Infection in the treatment area Tendency toward keloid scarring or allergic reactions Long-term corticosteroid therapy or other medication considered incompatible with the procedures Hyaluronic acid filler or botulinum toxin injections in the treatment area Tattoo or permanent makeup in the treatment area Invasive aesthetic procedures within the previous 5 months Failure to meet the inclusion criteria