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NCT07796555
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Conditions: Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Sex: All
Ages: 6 Months – 90 Years
Healthy volunteers: No
Enrollment: 100
Sponsor: Sohag University
Summary
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S. aureus are one of the most clinically significant opportunistic pathogens, causing a wide range of community and healthcare-associated infections. These infections vary from superficial skin and soft tissue infections to severe invasive diseases, including bacteremia, infective endocarditis, pneumonia, osteomyelitis, and device-associated infections .
Eligibility Criteria
Inclusion Criteria:
* Patients of any age diagnosed with postoperative SSIs.
* Clinical isolates from SSIs identified as MRSA.
Exclusion Criteria:
* Any microorganism isolated from SSIs other than MRSA.
* Prior administration of postoperative antibiotics
Source: ClinicalTrials.gov (NCT07796555). StuddyBuddy aggregates publicly available trial information.
