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Not Yet Recruiting NCT07797114

Predictors of Mortality in Cirrhotic Patients With Acute Kidney Injury

Conditions: AKI in Cirrhosis

Sex: All
Healthy volunteers: No
Enrollment: 100
Sponsor: Assiut University

Summary

Acute kidney injury (AKI) is a common and severe complication in patients with liver cirrhosis, significantly increasing the risk of short-term mortality. Early identification of clinical and laboratory predictors of mortality in these patients is crucial for risk stratification and optimizing clinical management. This study aims to identify the key clinical parameters (such as the presence of ascites, hepatic encephalopathy, and hemodynamics) and laboratory markers (such as serum creatinine, bilirubin, albumin, sodium, and INR) that predict short-term mortality in cirrhotic patients presenting with AKI. The findings will assist clinicians in recognizing high-risk patients early and tailoring targeted therapeutic interventions .

Eligibility Criteria

Inclusion Criteria: * Adults aged ≥ 18 years. * Hospitalized cirrhotic patients who develop AKI and mortality occurs within 30 days of the development of AKI Exclusion Criteria: * Patients younger than 18 years * Patients with HIV infection. * Patients with previous liver transplantation. * Patients with incomplete clinical or laboratory data * Patients with end-stage chronic kidney disease on maintenance dialysis. * Patients with acute liver failure without underlying liver cirrhosis

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07797114). StuddyBuddy aggregates publicly available trial information.