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NCT07805109
Subclinical Renal Dysfunction in Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis, Renal Dysfunction, Chronic Kidney Diseases
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 120
Sponsor: Assiut University
Summary
This comparative cross-sectional study aims to determine the prevalence of subclinical renal dysfunction in patients with rheumatoid arthritis and to evaluate its association with disease activity and inflammatory markers compared with age- and sex-matched healthy controls at Assiut University Hospitals.
Eligibility Criteria
Inclusion Criteria:
* Age 18 years or older
* For patient group: Diagnosis of rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria
* For control group: Age- and sex-matched apparently healthy individuals with no history of autoimmune disease or chronic kidney disease
* Willingness to provide written informed consent
Exclusion Criteria:
* Known chronic kidney disease
* Acute kidney injury
* Diabetes mellitus
* Uncontrolled hypertension
* Active urinary tract infection
* Pregnancy
* History of obstructive uropathy or renal stones
* Systemic lupus erythematosus or other connective tissue diseases
* Malignancy
* Patients on maintenance hemodialysis
Source: ClinicalTrials.gov (NCT07805109). StuddyBuddy aggregates publicly available trial information.
