Leukocyte Glucose Index and Severity of Diabetic Ketoacidosis

This prospective cohort study aims to evaluate the relationship between admission Leukocyte Glucose Index (LGI) and the severity of diabetic ketoacidosis, as well as the presence of diabetic microvascular complications, among adult patients at Assiut University Hospitals.

Inclusion Criteria: * \- Age 18 years or older * Known diabetes mellitus or newly diagnosed diabetes presenting with DKA * Fulfilling accepted clinical and biochemical diagnostic criteria for diabetic ketoacidosis * Written informed consent Exclusion Criteria: * \- Active infection or sepsis judged likely to substantially influence leukocyte count independently of DKA * Hematological malignancy or disorder affecting leukocyte count * Recent chemotherapy, G-CSF, or other treatment markedly altering leukocyte count * Pregnancy * Concurrent acute inflammatory or autoimmune disease likely to affect inflammatory indices * Systemic corticosteroid use before presentation when clinically significant * Incomplete clinical or laboratory data preventing LGI calculation or DKA severity assessment * Refusal to participate