Improving the Treatment of Acute Uncomplicated Diverticulitis in Routine Care

Acute uncomplicated diverticulitis is often treated with antibiotics, although current evidence shows that antibiotics are not always necessary. This study will evaluate whether a more standardized approach to treatment can reduce unnecessary antibiotic use without increasing the risk of treatment failure. The study will compare patients treated before and after the new treatment approach is introduced in participating Swiss hospitals. Information on treatment, hospital admissions, complications and recurrence of diverticulitis will be collected. Patients will be followed for up to 24 months.

Inclusion Criteria: * Age 18 years or older * CT-confirmirmed acute uncomplicated diverticulitis of the left colon * Ability to provide informed consent for participants in the prospective phase Exclusion Criteria: * Complicated acute diverticulitis, defined as diverticulitis with abscess, perforation (free air), fistula, or distant free fluid * Diverticulitis of the right or transverse colon -.Alternative diagnosis explaining the participant's symptoms * No possibility of completing the 90-day follow-up * Inability to provide informed consent for the prospective phase