Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash

This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash). Following a baseline oral health assessment, participants will use the assigned mouthwash twice daily for 4 consecutive days while refraining from all mechanical oral hygiene practices (e.g., tooth brushing). The trial follows a 2-phase crossover design, where participants use one mouthwash in the first phase and the other in the second phase, separated by a 15-day washout period.

Inclusion Criteria: * Individuals with \> 20 teeth present, with a minimum of 5 teeth per quadrant. * Individuals \>18 years of age Exclusion Criteria: * Individuals with systemic diseases (ASA III o IV). * Individuals with systemic diseases or undergoing pharmacological treatment that may modify gingival health. * Individuals with periodontal disease (probing depth \> 5mm and/or clinical attachment loss \>2mm). * Individuals currently under orthodontic treatment. * Individuals with removable dental prostheses. * Individuals with known allergies to any ingredient in the study mouthwashes. * Individuals presenting with oral mucosal lesions. * Individuals who have used antibiotics, antifungals, corticosteroids, or contraceptives within 3 months prior to the study. * Individuals who have used chlorhexidine mouthwash or any other oral antiseptic within 15 days prior to the start of the study. * Individuals with any active carious lesions or any cervical restorations present on any tooth.