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Completed
NCT07825961
Efficacy of Melatonin in the Treatment of Diabetic Nephropathy Compared With Folic Acid
Conditions: Melatonin, Diabetic Nephropathy, Folic Acid
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: No
Phase: NA
Enrollment: 75
Sponsor: Tanta University
Location: Tanta University Tanta El-Gharbia
Summary
The current study aims to investigate and compare the anti-inflammatory effects of melatonin versus folic acid in patients with diabetic nephropathy.
Eligibility Criteria
Inclusion Criteria:
* Adults aged 18-75 years.
* Patients with a confirmed diagnosis of Type 2 diabetes and diabetic nephropathy, as indicated by an elevated urine albumin-to-creatinine ratio (UACR ≥ 30 mg/g) or a decreased estimated glomerular filtration rate (eGFR \< 60 mL/min/1.73 m²).
Exclusion Criteria:
* Patients who are expectant or breastfeeding.
* Have significant comorbidities.
* Have rapidly declining renal function.
* Have acute kidney injury.
Source: ClinicalTrials.gov (NCT07825961). StuddyBuddy aggregates publicly available trial information.
