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NCT07827924
Designing a Large Language Model Architecture for Shared Decision Making and Informed Intentions
Conditions: Shared Decision Making, Health Literacy, Patient Participation, Artificial Intelligence
Sex: Female
Ages: 40 Years – 70 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 330
Sponsor: Harding Center for Risk Literacy
Summary
This study investigates a novel, agentic Large Language Model (LLM) architecture designed to facilitate Shared Decision-Making (SDM) in healthcare. While patients increasingly use standard LLMs for health information, these models often struggle with multi-turn conversations and fail to adapt to varying reading levels, disadvantaging vulnerable groups. By utilizing an agentic state-machine, this project aims to overcome common LLM deficits-such as context loss and uncritical agreement-to ensure clinically accurate, participatory patient conversations. The study evaluates whether this architecture improves informed decision-making compared to standard LLMs, particularly for patients with low health literacy.
Eligibility Criteria
Inclusion Criteria:
* Biological sex: Female.
* Age: 40 to 70 years old.
* Country of residence: United States (US) or United Kingdom (UK).
* Language: Native English speaker (English as first language).
* Registered and verified user on the academic research platform Prolific.
* Able to read, understand, and provide informed consent digitally.
Exclusion Criteria:
* Individuals who do not meet the automated pre-screening criteria on the Prolific platform.
* Inability to use or access a computer, smartphone, or internet browser required to complete the digital study.
Note: Quotas will be enforced during recruitment to ensure a 50/50 stratified split between participants with and without university entrance qualifications to guarantee variance in educational backgrounds. Once a quota is filled, further participants matching that educational profile will be excluded.
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Source: ClinicalTrials.gov (NCT07827924). StuddyBuddy aggregates publicly available trial information.