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NCT07828977
Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway Ventilation
Conditions: Airway Management, Neuromuscular Blockade, General Anesthesia
Sex: All
Ages: 20 Years – 65 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 96
Sponsor: Korea University Guro Hospital
Summary
This prospective, randomized, double-blind study aims to evaluate the effect of different degrees of neuromuscular blockade on the performance of a video laryngeal mask airway (LMA) during general anesthesia. Participants will be randomly assigned to receive rocuronium at 0, 0.3, or 0.6 mg/kg, corresponding to 0, 1, or 2 times the ED95, respectively. The primary outcome is oropharyngeal leak pressure measured after LMA insertion. Secondary outcomes include LMA insertion conditions, insertion time and number of attempts, laryngeal view, respiratory parameters, and postoperative airway-related complications.
Eligibility Criteria
Inclusion Criteria:
* Scheduled for elective surgery under general anesthesia with a video
* laryngeal mask airway
* Expected duration of surgery less than 3 hours
* Surgery performed in the supine position
* Provision of written informed consent
Exclusion Criteria:
* Symptoms or signs of upper respiratory tract infection
* Increased risk of pulmonary aspiration
* Anticipated difficult airway
* Limited mouth opening (\
Source: ClinicalTrials.gov (NCT07828977). StuddyBuddy aggregates publicly available trial information.