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Not Yet Recruiting NCT07829536

Silent Deployment and Prospective Evaluation of Zhunxin Agent for Emergency Chest Pain Assessment

Conditions: Chest Pain Center, Chest Pain

Sex: All
Ages: 18 Years – N/A
Enrollment: 10000
Sponsor: Peking University Health Science Center

Summary

The goal of this prospective, multicenter observational study is to evaluate how well Zhunxin Agent, an artificial intelligence system for chest pain assessment, performs in real-world emergency department settings. The study will include people who receive routine care for acute chest pain at participating hospitals. The main questions this study aims to answer are: 1. How accurately can Zhunxin Agent identify serious causes of acute chest pain during routine emergency care? 2. How well can Zhunxin Agent distinguish people at different levels of clinical risk? Zhunxin Agent will run in silent mode using clinical information collected during routine care. Its predictions will not be shown to treating clinicians and will not affect clinical decisions, diagnostic tests, or treatment. Researchers will compare the predictions made by Zhunxin Agent with the final clinical diagnoses established through routine medical care. Participants will: 1. Receive usual emergency care according to local clinical practice 2. Have routinely collected clinical data analyzed by Zhunxin Agent in the background 3. Receive no additional treatment or clinical intervention based on the Agent's predictions

Eligibility Criteria

Inclusion Criteria: * Participants aged 18 years or older. * Participants presenting to a participating emergency department with acute chest pain, chest discomfort, or other symptoms that prompt clinical evaluation for an acute chest pain-related condition. * Participants undergoing an electrocardiogram as part of routine clinical care during the index emergency department encounter. * Participants with at least one electrocardiogram that can be processed by Zhunxin Agent during the index emergency department encounter. * Participants with the routinely collected clinical information required for Zhunxin Agent to generate a valid prediction. * Participants presenting to a participating study site during the prospective study period. Exclusion Criteria: * Participants whose emergency department presentation does not involve evaluation for acute chest pain. * Participants without an electrocardiogram obtained during the index emergency department encounter. * Participants for whom the electrocardiogram or other required input data are missing, corrupted, technically inaccessible, or otherwise unusable such that Zhunxin Agent cannot generate a valid prediction. * Duplicate records corresponding to the same emergency department encounter. * Participants whose clinical data cannot be used for research because of withdrawal of consent, refusal of data use where applicable, or other ethical, institutional, or regulatory restrictions.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07829536). StuddyBuddy aggregates publicly available trial information.