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Not Yet Recruiting NCT07832890

Sepsis Associated Liver Injury in Pediatric Sepsis at Assiut University Children's Hospital - 2026

Conditions: Sepsis, Liver Injury

Sex: All
Ages: 1 Month – 18 Years
Healthy volunteers: No
Enrollment: 158
Sponsor: Assiut University

Summary

This prospective cohort study aims to determine the incidence of sepsis-associated liver injury (SALI) among pediatric patients with sepsis admitted to Assiut University Children's Hospital and to evaluate its association with clinical outcomes.

Eligibility Criteria

Inclusion Criteria: * Age from 1 month to 18 years * Sepsis diagnosed according to the Phoenix Sepsis Score (≥2 points) * Written informed consent from parents or legal guardians Exclusion Criteria: * Neonates less than 28 days of age * Pre-existing chronic liver disease (cirrhosis, biliary atresia, metabolic liver diseases, autoimmune hepatitis, acute viral hepatitis, previous liver transplantation, malignancy with hepatic involvement, or drug-induced liver injury present before admission)

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07832890). StuddyBuddy aggregates publicly available trial information.