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Completed
NCT07841366
Compairing Micro Needling With Phenytoin Versus Microneedling Alone on Striae Alba
Conditions: Treatment of Striae Alba
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 30
Sponsor: Al-Azhar University
Location: Al-Azhar University, Faculty of Medicine for Girls Cairo Cairo Governorate
Summary
The aim of this study is to evaluate the efficacy and safety of Microneedling with Phenytoin versus Microneedling alone for the Treatment of Striae alba.The study is a comparative study which will be carried on 30 patients with Striae alba. Each patient will receive four sessions three weeks apart of the following treatment: -Right side: striae on the right side will be treated by microneedling with depth (2 mm)with topical phenytoin 2% solution. -Left side: striae on the left side will be treated by microneedling alone with depth (2 mm) .
The follow up will be during each session and 1 months after the last session. For treated striae alba, Microneedling will be done under aseptic conditions using isopropyl alcohol 70%.
Eligibility Criteria
Inclusion Criteria:
* Patients with stria alba.
* The patient's age ≥18 years.
* Both sex male and Femal patients
* At least 3 stria
Exclusion Criteria:
* Pregnancy or lactation.
* Keloid or hypertrophic scar tendency
* Active skin infection at treatment site
* Use of isotretinoin within the past 6 months
* Bleeding disorders or anticoagulant therapy
* History of hypersensitivity to phenytoin
* Chronic systemic diseases affecting wound healing (e.g., uncontrolled diabetes)
* Previous striae treatment within the last 6 months
* Unrealistic expectations or poor compliance
* Premalignant or malignant lesions in the treatment area
Source: ClinicalTrials.gov (NCT07841366). StuddyBuddy aggregates publicly available trial information.