Intermediate Outcomes of HFrEF Patients on Guideline-Directed Medical Therapy

Conditions: Heart Failure With Reduced Ejection Fraction, HFrEF - Heart Failure With Reduced Ejection Fraction

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 250

Sponsor: Assiut University

Summary

This prospective observational study aims to evaluate intermediate clinical, renal, and functional outcomes in patients with heart failure with reduced ejection fraction treated with contemporary guideline-directed medical therapy over a 6 to 12 month follow-up period.

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Diagnosis of chronic HFrEF with LVEF ≤ 40% documented by echocardiography * Stable on or planned initiation of guideline-directed medical therapy * Ability to provide informed consent Exclusion Criteria: * \- Acute decompensated heart failure requiring intravenous inotropes at enrollment * End-stage renal disease on dialysis * eGFR less than 20 mL/min/1.73 m² at baseline * Severe primary valvular disease requiring immediate intervention * Life expectancy less than 6 months due to non-cardiac illness

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07845201). StuddyBuddy aggregates publicly available trial information.