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Recruiting NCT07852273

Investigating the Effect of the Non-nutritive Sweetener Sucralose in Inflammatory Bowel Disease

Conditions: Inflamatory Bowel Disease, Crohn Disease (CD)

Sex: All

Ages: 18 Years – 75 Years

Healthy volunteers: Yes

Phase: NA

Enrollment: 40

Sponsor: Case Western Reserve University

Location: UH Minoff Health Center Chagrin Falls Ohio

Summary

This study will focus on the commonly used non-nutritive sweetener (NNS) sucralose (2 sachets/day resulting in daily dose: sucralose 2.5mg/kg) and its role in changing the gut microbiota in humans with Inflammatory Bowel Disease (IBD), compared to healthy non-IBD individuals. We will focus on studying IBD patients affected with Crohn's Disease (CD) as a proof of principle that could be tested later in other IBD subtypes (ulcerative colitis or others specific surgical conditions).

Eligibility Criteria

Inclusion Criteria: * Age range from 18 to 75 years * Male or female * Documented diagnosis of Crohns disease. CD outpatients in remission; Harvey Bradshaw- index in remission (\

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07852273). StuddyBuddy aggregates publicly available trial information.