Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder

The investigators aim to examine the effect of transcranial focused ultrasound (tFUS) on brain activity and cocaine craving in adults with cocaine use disorder.

Inclusion Criteria: * Between 18-45 years of age * Uses cocaine as a primary drug at a minimum frequency of 1x/mo; any period of abstinence within the past month does not exceed 1 week Exclusion Criteria: * Not between 18-45 years of age * Cocaine is not used as a primary drug, is used at a frequency of less than 1x/mo, and/or a period of abstinence lasting longer than 1 week has occurred within past month * Present/lifetime history of primary psychosis or Bipolar Disorder (DSM-5 criteria, SCID-5, SCID-5-PD, YMRS\>10), present suicidal ideation, or current depressive episode * History of head injury, neurological (e.g., epilepsy), pervasive developmental disorder (e.g., autism), systemic medical disease and treatment (medical records, participant report) * Family history of epilepsy * Use of substances with seizure risk (e.g., stimulants), benzodiazepines, and dopaminergic psychotropic medications in the past month * Mini-Mental State Examination (MMSE) score (cognitive state) \